Physiology before Pharmacology for Healthy Blood Pressure

My interview with Dr. Russell Jaffe

Dr. Russell Jaffe

Heart Support

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This is an important interview on a couple of levels. First because Dr. Jaffe stresses the importance on nutrition, diet and lifestyles for healthy blood pressure and as a first line defense. Secondly he discusses some of the deficiencies in the medical approach of controlling blood pressure with pharmaceutical drugs and the failure of many doctors to consider the lifestyle factors. In this interview we will discuss how to maintain a healthy blood pressure by lifestyle choices before turning to pharmaceutical drugs.

I think it is a fair question to ask “What is missing in the current medical model for treating high blood pressure?” There are several items for you to consider. You can’t make an  informed decision if you don’t understand your circumstances and options.

  • What is your blood pressure in the doctor’s office compared to blood pressure taken at different times, places and circumstances? Do you have white coat syndrome, which is when your blood pressure is up just because you are in the doctors office? What is your blood pressure when you are relaxed and at home? You need to know if your BP is up all the time or not.
  • What are your numbers compared on the scale of low to high on average. Are you 120, 140, 160, 180, etc? The degree of risk is lower the closer you are to “normal”. If you are near normal, then the opportunity to improve without drugs is greater. Where do you fit on the scale? In either case lifestyle choices are critical. You must support your body and give it what it needs. You must nourish the tissues involved especially the blood vessels.
  • mineralsWhat are the lifestyle choices that can affect BP? Diet, exercise, supplementation, stress management, deep breathing, good sleep are very important. For the average healthy person these interventions are likely to be very successful. For someone with health complications or very high BP, the lifestyle choices are still important, but as an adjunct to medical care. In either case, give your body a chance to repair and restore through lifestyle and nutritional supplementation. This is what we cover in this interview with Dr. Jaffe.
  • What are the benefits and risks associated with pharmaceutical interventions? If you don’t understand this you cannot know if a medication is likely to help and what are the side effects.

You can listen to Dr. Jaffe’s previous interviews on the eight predictive biomarkers and learn how to evaluate your health risks.

LEARN ABOUT THE NNT (Numbers Needed to Treat) NOTE: This is my soapbox and not part of Dr. Jaffe’s interview.

When I learned about the NNT, it change my world view about benefits and misuse of pharmaceutical drugs. I have discussed this in past interviews. I think you should understand the NNT especially for any drugs you take. Basically the NNT for any drug represents how many people need to be treated in order to benefit one person. This may seem confusing at first, but when you understand what the NNT means, you will have a powerful new way to evaluate the benefits versus risks of drugs you take or are considering.

Most people think that drugs are highly effective for most people. People assume that BP drugs will reduce the number of heart attacks, strokes and/or deaths in a significant way. It is hard to accept the fact that these drugs are not very effective and that this is revealed in the studies. But doctors and consumers are never told about the actual benefit or more accurately the lack of benefit. The benefits are disguised and manipulated to exaggerate the benefits by reporting only the relative risk reduction.

I recommend that you visit a site called There you can research many drugs in order to understand the risks versus the benefits. In the case of BP drugs for people with blood pressure of 170, you have to treat 125 people for 5 years to prevent 1 death. You have to treat 88 people for 5 years to prevent 1 stroke and you have to treat 100 people for 5 years to prevent 1 heart attack. So the drugs are not very effective and you have to treat a lot of people to have a benefit for 1 person. It is no wonder that our nation is over-medicated. People with modestly high BP with no cardiovascular issues are not likely to receive any benefit. 10% of patients will discontinue treatment due to side effects of the medication. Here is an excerpt from

Blood Pressure Medicines for Five Years to Prevent Death, Heart Attacks, and Strokes

Efficacy Endpoints: Mortality, stroke, coronary artery disease, cardiovascular events

Harm Endpoints: Stopping medication due to adverse events

Narrative: Hypertension affects almost 29% of adults in the United States, most of whom are taking medication to lower their blood pressure. Blood pressure control has been shown to reduce the chances of developing cardiovascular problems and stroke (Mancia et al, 2009), however these reductions are derived from studies of patients with moderate or severe hypertension, and those with a history of prior cardiovascular events such as heart attack or stroke. However, evidence has been unclear on whether pharmacological treatment for previously healthy patients with ‘mild’ hypertension is beneficial.

This review included four randomized-controlled trials enrolling 8,912 subjects with mild elevations in blood pressure (systolic blood pressure 140-159 or diastolic blood pressure 90-99) without preexisting cardiovascular disease. 

At a period of four to five years follow up, no differences were seen in mortality, cardiovascular events, CAD, or stroke. Approximately 9% more patients in the treatment arms withdrew due to medication side effects. End excerpt.

Let that sink in. Five years of being medicated and there is NO difference in outcomes!! This is one of the dirty secrets of the pharmaceutical industry. Their drugs are less effective than we are told. The harms are greater than we are told. 

PERQUE Maganesium Plus Guard

So ask yourself, are you the 1 person, or are you among the many? How likely is it, that you will benefit from medications? Are you someone who takes care of themselves otherwise. A person who is well nourished will do better than someone who isn’t. People who seek to repair, restore and maintain good health will always be at lower risk.

There is more to the story. In addition to the NNT, there is also the NNH (Number Needed to Harm), NNH is how many people are treated for every 1 person who has an adverse event. In the case of BP drugs that number is about 1 in 10. 

Two other numbers you should understand is Relative Risk Reduction (RRR) and Absolute Risk Reduction (ARR). Ultimately it is the Absolute Risk Reduction that you want to know. The NNT reveals the ARR. If you were told that a drug is effective at a rate of 1 out of 100, would you consider that an effective drug? Probably not. When you realize that the very best drugs we have are effective for 1 in 4 to 1 in 10 and that most drugs are only effective for 1 in 50 to 1 in hundreds or thousands, it changes ones perspective.

This does not suggest that you should not use prescribed medications. It is to suggest that you should become informed about the true risks and benefits of any medications you take or are considering. If you need to find a practitioner to help you, contact for a referral to a knowledgeable nutritional practitioner.

About Dr. Jaffe
Dr. Russell M. Jaffe received his BS, MD and Ph.D from the Boston University School of Medicine in 1972. He completed residency training in clinical chemistry at the National Institutes of Health (1973 – 1976), remaining on the permanent senior staff until 1979. He is board certified in Clinical Pathology and in Chemical Pathology. On leaving NIH Dr. Jaffe began a journey that sought to support the emerging field of Integrative and Regenerative Medicine.

Dr. Jaffe is CEO and Chairman of PERQUE Integrative Health (PIH). His dedication to the application of primary prevention and his commitment to providing superior nutraceuticals and autoimmune testing with clinical evidence of superior efficacy has made him a sought after speaker and leader in his chosen field.




Whey protein is one of the most easily assimilated supplemental proteins.

My Interview with Dr. Audrey Ross

Joint & Muscle Support

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More consumers are seeking to boost protein consumption and whey protein is perhaps the most popular and for good reasons. We use protein powders in our home and we have found that whey protein is our preferred source of supplemental protein.

One of the great advantages that we have now as consumers is that nutritional science continues to evolve and wonderful products based on that science are widely available. That’s the good news. The bad news is that there are many products that have flooded the market with inferior, low quality products. The sad news for the consumer is that it is challenging to know what to look for.

In this interview with Dr. Audrey Ross, we will discuss the benefits and distinctions of whey protein. We will also discuss innovative ways to enhance your protein smoothie. We will explore Biochem Science by Nature Whey Protein and some of the company’s recent innovations. By way of full disclosure, this is the protein that we use and recommend to others. I’m happy to recommend Biochem because I know what sets their products apart from the rest. It’s the distinctions between one company and another, one product from another and the ingredients that determine quality and effectiveness. We’ll explore some of those distinctions in the interview.

What is Whey Protein?

100% Grass Fed Cows

Whey is product of cheese production. The protein found in whey is highly biologically available to humans. Whey protein contains a complete 20 amino acid profile which provides the building blocks for the body.* Whey protein contains essential, non-essential and branched chain amino acids. Whey can be found in two forms: concentrate (containing the fat, cholesterol and lactose as found in dairy) and isolate form (most of the fat, cholesterol and lactose are removed). This is one of those distinctions to look for.

I mentioned that we use and recommend Biochem Science by Nature Whey Protein. It is because this brand meets our requirements. We are always looking for the best products we can find for our personal use. We do what I recommend to you and that is to research the company, products and ingredients. When we choose a brand it is usually because we understand some of those distinctions. You can compare them to whatever other protein you are using. You get to choose what is important to you. Ultimately the best product is the one that works best for you. You can always experiment with different brands and choose that which suits you. This is simply the one brand that we like and I’m happy to tell you why.

Biochem Science by Nature Whey Protein Isolate (Dr. Ross discusses these in greater detail in the interview)

  • Provides 20 grams of high quality protein per serving
  • 100% from grass fed cows
  • 99% Undenatured and dual filtered
  • 99% lactose free (the only one in the top 3 brands
  • Non GMO, gluten free, soy free, vegetarian and kosher certified.
  • 5 star rating from the Clean Label Project
  • Free of artificial hormones including rBST and rBGH
  • Mixes easily and taste good
  • Supports muscle health*
  • Supports immune health*
  • Includes immune fractions like immunoglobulin and lactoferrin
  • Made and sourced in the USA (Biochem does not use foreign sourced whey)
  • Also available as USDA Organic Whey Concentrate

These things make a difference. Biochem Science by Nature Whey Protein sets the highest standard through rigorous ingredient testing for quality and purity.  “Science by Nature” means incorporating modern technologies to extract the best from nature through gently processing providing the highest quality final product.  They can assure the consumer that this is a true representation because of multiple 3rd party certifications. This is one of the important ways to confirm the status, quality and commitment of the companies you purchase from.

Enhancing your smoothie

A lot of consumers are seeking to enhance their smoothie or other drinks with additional nutrients. The convenience of being able to augment your protein smoothie, juice, water, etc.  is highly desirable. There are now 4 new enhancer powders for you to consider. Biochem Enhancers can be mixed and matched to target your ever changing daily nutritional support. These are especially nice if you don’t like tablets or capsules or for the supplement weary who just don’t want to take more tablets.  The four enhancer options (below) allow exceptional versatility when looking for additional nutrition.

The easiest way to know if this is right for you is to try it. If you like what Biochem Science by Nature does as a company, and then you can feel confident to try their products. This is how you discover the best products. The first step is to know about the company. Then you can experiment until you discover for yourself what works best for you.

I can’t express this enough: There are many products and brands available with varying levels of quality. It is naive to think that inexpensive no name products are equal to products that undergo rigorous testing and 3rd party certification. Good companies go far above minimum standards in order to create the best products. They want the consumer to understand this. Certifications and transparency are the hallmarks of good companies. If these are important to you then do your homework. Be a responsible consumer. This is your body, your money and your journey of discovery. Invest wisely and you will be rewarded. Learn more and you will make better choices. Better choices lead to better outcomes.

List of all Country Life Vitamins and Biochem Science By Nature Interviews.

Dr. Audrey Ross, ND
Dr. Ross works for Country Life Vitamins and Biochem Science by Nature as an educator. She has a PhD in Naturopathy as well as a degree in Marketing. Dr. Ross ran a naturopathic consulting practice in Texas and worked with medical doctors, providing nutritional consultations for patients. Dr. Ross has a passion for teaching and has conducted seminars on nutrition, weight loss, stress reduction, etc. She co-authored a book on female hormone management in 2000. Her passion and knowledge bridges the divide between allopathic and naturopathic health care.
Biochem Science by Nature


292 – Astaxanthin: Nature’s Most Potent Antioxidant for Skin

Skin is our largest organ and our first line of defense against environmental exposures like damaging UV rays, pollutants and microbes that can leave skin feeling dry and showing fine lines. Topical applications, like serums and creams, reach the surface of the skin but can’t get down into the deeper layers that contribute to skin’s elasticity and nourishment. Taking astaxanthin orally promotes healthy skin from the inside out.

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291 – Nutritional Support for Auto Immune Issues – My Interview with Laurel Sterling

I have a strong personal interest in this topic. I have reported on this frequently because my wife, Debbie has been challenged with Rheumatoid Arthritis for over 40 years. In her case it was severe. She left her job as a teacher in 1989 and never was able to go back to work. She spent the next 15 years just trying to survive day to day by consuming 8 narcotic Darvocet doses each day. Those were tough days. So we personally know the challenge of auto immune breakdown. I have great empathy for those who suffer and their families. Our lives were turned around in 2003. There were two thing that changed her course in the most dramatic ways, drugs and nutrition.

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290 – Thyme Extract for Acne, Eczema and More – My Interview with Andrew Klenert

Thyme Out is effective and fast alternative for Eczema, Psoriasis, Acne, Dermatitis, Rosacea, Cold Sores, Pet Rashes, Bug Bites, Fungus, Poison Ivy, Any Skin Inflammation! This is a pretty impressive claim. That’s what I first thought when I learned about Thyme Out Skin Remedy. My second thought was “how do we know that those are the benefits of Thyme extract?” So I discovered the answer in conversations with Andrew Klenert. You’ll learn the answer as well in this interview with Andrew.

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289 – Nutritional Support for Eye Health – My Interview with Anthony Thomas

In this interview with Anthony Thomas, we are discussing what are called “macular carotenoids”. Studies have shown that increasing the consumption of macular carotenoids significantly improved serum levels with the benefits as noted above. The macular carotenoids are lutein, zeaxanthin, and mesozeaxanthin. We will also consider the benefits of astaxanthin. In this discussion we will consider the benefits of trademarked, branded, clinically studied nutrients.

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288 – The Nutritional Power of Green Foods – My Interview with James LaValle

Greens and sprouted foods have been a part of the human diet for thousands of years. The animals consumed for food also consumed green grasses and leaves. The insects consumed green plants. In the ocean, krill eat green algae, sardines eat krill and so on up the food chain. It all starts with energy from the sun becoming plants on the land and algae in the ocean. These greens eventually become the omega-3 fatty acids that are so important. This is one reason why grass fed beef is better than grain fed beef.  It’s one reason why wild ocean fish are better than farm raised fish. It’s one reason why we are encouraged to eat green foods.

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287 – The Healing Power of Topical Silver Gel – My Interview with Dr. Robert MacCuspie

I love Sovereign Silver First Aid Gel. We have used Sovereign Silver products in my home for nearly twenty years. It is the only silver product I use and the only one I recommend. This is one case where there is no other silver that I know of that meets this high standard. Most companies that sell silver products do not manufacture their own silver products. They are made by some other company. So you have to dig deep to compare silver products. Sovereign Silver has done the analysis of virtually every other silver product in the marketplace and you can literally see the difference. You can review all of this at the Sovereign Silver website.

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286 – Nutrition for Your Brain – Part 2 – My Interview with Neil E. Levin

In this interview with Neil E. Levin, we are looking at nutrients that can influence mood, stress, sleep and tension issues. We are also considering nutrients for memory, brain acuity and concentration. There are often multiple factors occurring at the same time. If you have everyday stress in your life, you may not be sleeping well. If you don’t sleep well, it’s hard to restore your brain and this may affect your mood. This could lead to nervousness. Any of these can affect your quality of life.

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285 – Coenzyme B-Complex for Energy – My Interview with Dr. Audrey Ross

In this interview with Dr. Audrey Ross, ND, we will discuss the importance of B-vitamins in human health. We will also discuss the newer forms of B-vitamins known as Coenzyme B-vitamins. Dr. Ross will also discuss several nutrients that are surprisingly also forms of B-vitamins. This is a good example of making distinctions in the marketplace. Many companies don’t use any of the newer forms of nutrients. Country Life Vitamins uses all 7 of the currently available Coenzyme forms of B-vitamins and was one of the first companies to develop a Coenzyme B-complex supplement.  This is why I wanted to speak with Dr. Ross about the role of B-vitamins and the importance of Coenzyme B-vitamins.

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