How well does your digestive system work?

Digestive Support

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The digestive process starts as soon as you place food in your mouth.  The saliva and chewing are the first steps to proper digestion of you food.  Present in saliva are some enzymes that start the process.  In the mouth also exist the presence of good and bad bacteria.  More on bacteria in a minute.

After chewing your food you then swallow.  When you swallow the food will travel the entire length of the GI (Gastrointestinal) tract by a process called peristalsis which is the muscular contractions designed to propel food forward.  This movement is sort of like a wave in the ocean.  Once swallowed the food travel down the throat and esophagus to the stomach.  The presence of food in the stomach initiates the production of acid, which is key in breaking down the food.

A little Digestive Trivia: How much acid on average will your stomach produce daily? Approximately 2 liters
After the food has been broken down in the stomach it moves on to the small intestines.  This is where food particles are digested and nutrients are extracted.  Whatever remains, is considered by the body to be waste.

More Digestive Trivia: How long are the small intestines? Approximately 20 feet
The so-called waste now enters the large intestines or as it is often referred  “the Colon”.  Here the water is removed from the waste and absorbed.  The remaining waste material is then eliminated through the rectum and anus.  In colon is lined with a protective mucosal barrier.  A healthy mucosal barrier protects the body from absorbing potentially harmful organisms and toxins.

What is a Probiotic?
The word Probiotic, according to the WHO (World Health Organization), means:

“Probiotics are living microorganisms, which, when administered in adequate amounts, confer a health benefit on the host.”

“Pro” means “For”
Biotic means “Life”
Probiotic means “Pro-Life”

In other words, probiotics are “good bacteria”.  Your native intestinal micro flora is your indigenous probiotics.  Probiotic supplements provide beneficial living bacteria, such as Lactobacillus and Bifidobactia, that help to support digestive balance and digestive health.

Many factors may contribute to an imbalance of your native gut flora such as diet, stress, illness, certain medications such as antibiotics, aging and much more.  Such an imbalance may contribute to digestive upset and may lead to other issues.

BacteriaThe concept of probiotics was born in the early 20th century when Russian scientist Elie Metchnikoff hypothesized about the use of fermented milk and using them to elicit health benefits for people that consumed the yogurt like fermented milk.  He concluded that the fermented milk product helped to “seed” the intestines with friendly beneficial bacteria.  By seeding the intestines with these friendly probiotic bacteria he found that it may help suppress the growth of bad bacteria or at the very least keep things in balance.  These fermented milks are the best examples of early probiotics.

Modern probiotics have become a great deal more convenient and in many cases possibly more powerful and even more focused.

What is a Prebiotic?
It is food for the probiotics.  These prebiotics actually help the probiotics grow and flourish.  They are extremely important in supporting the survival of probiotics.

Prebiotics important properties include:

  • Healthy bacteria- building potential
  • They are actually fiber
  • They are indigestible by bad bacteria
  • They are food for the probiotics
  • The three most common prebiotics are Inulin (used in all Probulin products), oligofructose, and polydextrose.

It is key when choosing a probiotic supplement that you look for prebiotic fiber like Inulin.

Why Probulin?

All Probulin®products are formulated by board certified Naturopathic Doctor Jason Mitchell along with prominent gastroenterologist, award winning author, founder of Kansas Medical Clinic and author of Probiotics For Dummies, Dr. Shekhar Challa.  Probulin produces  quality probiotic supplements. Probulin represents “The Next Generation in Probiotics.”  Probulin products proudly feature the following:

Shelf Stable
Include a minimum of 7 to 12 strains of beneficial probiotic bacteria in every product.
Includes the patent pending MAKTrek 3-D Probiotic Delivery System
Gluten Free
Soy Free
Wheat Free
Dairy Free
Magnesium Stearate Free
Vegetarian Capsules
All beneficial probiotic strains used are documented strains
All formulations are put together and based on scientific research
Each Probulin® product is designed to support digestive health and digestive balance


What is MAKTrek 3-D Probiotic Delivery System?
The MAKTrek 3-D Probiotic Delivery System provides significant safeguards that may ensure better survival of the living beneficial probiotic bacteria.  The following are the 3 D’s of the MAKTrek 3-D system:

  • 1st – Two Step Acid Protection: The probiotic bacteria are enrobed by an extract of Brown Seaweed (Lessonia nigrescens) called complex marine polysaccharides. Once blended the final powder is encapsulated. When the capsule is swallowed it will come in contact with the stomach acid.  The acid will then dissolve the capsule.  The complex marine polysaccharides will form a secondary internal capsule protecting the living probiotic cells from the acid.
  • 2nd – In-Transit Buffering: This step is a proprietary all natural buffering system that helps to support the in-transit digestive environment condition.  Probiotic cells prefer balance and this system supports this balance.
  • 3rd – Additional Safeguards: The researched and documented strains used are naturally equipped to handle exposure to some common environmental elements that can and do make survival difficult for these beneficial probiotic bacteria. The MAKTrek 3-D Probiotic Delivery System has been scientifically studied using a specified stomach acid exposure simulation.  During this simulation the MAKTrek 3-D protected probiotic supplement showed greater survival than simply acid protection alone.

About Jason Mitchell ND, CEO
Dr. Jason Mitchell grew up in the natural products industry and being exposed at such a young age to the value of healthy eating and natural living has shaped his ideology on living a higher quality of life.  Dr. Mitchell has spent the last 15 years of his professional career developing over 200 industry leading dietary supplements.  Before becoming the Chief Executive Officer for Probulin and its family of companies he was most recently the Chief Science Officer and one of the managing executives for Country life Vitamins.

Dr. Mitchell is a board certified Naturopathic Doctor and member of the American Naturopathic Medical Association as well as a member of the Certified Natural Health Professionals.



Homocysteine is a predictive biomarker for cardiovascular health.

Heart Support

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This is our second interview in a series of eight predictive biomarker tests with Dr. Russell Jaffe. Our previous interview covered Hemoglobin A1c. There are six more to go. These eight predictive biomarker test enable you to measure, evaluate and change the status of those biomarkers. It is then possible to change the status of one’s health, sometimes dramatically. Predictive biomarkers provides a roadmap for you to focus on.

When it comes to nutrition, stop thinking in terms of disease. Nutrition does not treat disease. Nutrition nourishes the body. And when nourishing the body you must provide high quality foods and supplements to achieve the best outcomes. Predictive biomarker tests reveal what you nutrients you need to consider. After each of these interviews with Dr. Jaffe, you will have a great foundation to consider the value of these tests for yourself.

In this interview Dr. Jaffe will discuss homocysteine. Even though I have known for decades of homecysteine as a cardiovascular risk, I admit I never quite understood the connection. So I am learning along with you the significance of homocysteine in human nutrition. The bottom line takeaway is that as your homocysteine levels increase, your odds of living 10 more years goes down. As with some other biomarkers there is a range of values with risk increasing as blood levels increase. Understanding homocysteine is especially important if you have cardiovascular risk.

What is homocysteine?
Homocysteine is an amino acid. Having elevated levels of homocysteine in the blood (hyperhomocysteinemia) is associated with atherosclerosis and blood clots.

Methionine Rich Foods

Homocysteine is made from methionine, another amino acid that is found in meat, fish, and dairy products. Vitamins B6 (pyridoxine), B12 and folic acid are required nutrients in this process. Methionine from foods are transformed into homocysteine in the bloodstream. Homocysteine is converted in the body to cysteine, with vitamin B6 facilitating this reaction. Homocysteine can also be recycled back into methionine using vitamin B12-related enzymes. If homocysteine cannot be converted into cysteine or returned to the methionine form, levels of homocysteine in the body increase.

This chemical byproduct of cell function, homocysteine, is a widely-recognized marker of cardiovascular risk, and looks at risk independently of other markers, like cholesterol. Homocysteine levels reflect a process that occurs within every cell in the body, known as methylation chemistry. Methylation and cell detoxification control the expression of our genetic material through DNA, RNA and protein replication. Homocysteine plays a role in destroying the lining of your artery walls, promoting the formation of blood clots, and also accelerates the buildup of scar tissue. High levels may increase the chance of heart disease and stroke, especially if you have other risk factors such as diabetes, high blood pressure, obesity, smoking, or family history.

When this process is not working properly, homocysteine levels are elevated; therefore, this marker reveals function or dysfunction on the most basic level.  Homocysteine levels are considered elevated when greater than 6 µmol/L. High homocysteine is associated with disorders ranging from heart disease and cancer to Alzheimer’s disease and osteoporosis. The good news is that elevated homocysteine levels reflect an imbalance correctable through diet and supplements. As homocysteine levels return to a more normal range, it indicates reduced risk.

Certain nutrients have been associated with supporting healthy homocysteine levels. Most notably B6, B12 and Folate. These and other nutrients help to normalize healthier homocysteine levels to produce healthier blood vessels and blood pressure. The benefit is a reduction in the risk of heart attack and stroke.

It’s bad enough when you have one biomarker that is severely out of norm. It is especially bad if you have multiple biomarkers out of norm that are revealing a body that is in crisis. If you need a health care professional who understands how to manage these issues you can contact PERQUE directly.

Contact PERQUE Integrative Health – – 800.525.7372. Here you can learn more about finding a PERQUE trained practitioner, research the 8 Predictive Biomarkers and PERQUE products.

Better Lab Tests Now
If you want to order your own blood tests you can contact Better Lab Tests Now. Better Lab Tests Now offers only the highest quality lab tests available and works exclusively with highly decorated labs that have been awarded in their field. All of the necessary research has been done for you. Their clear and straightforward system allows you to choose the tests you need without the hassle of dealing with insurance companies. They offer food intolerance tests, hormone tests, and more. Please note that testing cannot be ordered from the states of New York, New Jersey, Rhode Island, Massachusetts, and Maryland due to those states’ laws prohibiting direct access testing for their residents. We hope this will change in the future. If you live in one of these states, contact your legislators and express your opinion about these restrictions on your access to these life enhancing tests.

Dr. Kilmer McCully
Dr. Jaffe refers several times to the groundbreaking research of Dr. Kilmer McCully. Dr. McCully first articulated the connection between homocysteine and cardiovascular disease. Unfortunately Dr. McCully’s research was overwhelmed by the cholesterol theory of heart disease. We now know that Dr. McCully was a pioneer and his research has been vindicated. Even so, we are still stuck with the relentless drive to prescribe cholesterol lowering drugs to the general public as necessary, safe and effective. Here is a link to a very interesting written interview with Dr. McCully by Dr. Richard Passwater. This interview will help you understand the background of our knowledge of homocysteine and why Dr. Jaffe considers this predictive biomarker to be so important.

About Dr. Jaffe
Dr. Russell M. Jaffe received his BS, MD and Ph.D from the Boston University School of Medicine in 1972. He completed residency training in clinical chemistry at the National Institutes of Health (1973 – 1976), remaining on the permanent senior staff until 1979. He is board certified in Clinical Pathology and in Chemical Pathology. On leaving NIH Dr. Jaffe began a journey that sought to support the emerging field of Integrative and Regenerative Medicine.

Dr. Jaffe is CEO and Chairman of PERQUE Integrative Health (PIH). His dedication to the application of primary prevention and his commitment to providing superior nutraceuticals and autoimmune testing with clinical evidence of superior efficacy has made him a sought after speaker and leader in his chosen field.


225 – Vitamin K for Bone and Cardiovascular Health – My Interview with Jolie Root

In this interview with Jolie Root we will cover some of the clinical studies and what they reveal. We will also discuss the various forms of vitamin K so that you will understand the distinctions. Like most nutrients, there are differences in various forms of nutrients and the often unique benefits. We will discuss the specific forms of vitamin K2 that were used in the studies.

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224 – Nutritional Support for Male Sexual Health – My Interview with James LaValle

There are many things which can interfere with sexual pleasure. One needs to do a careful and comprehensive look at what could be influencing factors. For an obvious example, there are many medications which can interfere in one way or another. Smoking and alcohol consumption can be a factor. Stress, anger, fear can certainly intrude and make it more difficult to sustain desire and performance. The point is that you have to consider other factors in your life and deal with them as well. A good nutritional product can help, but it cannot fix the other issues that are under your control. Strive to understand what are your influences and make changes where you can.

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223 – Predictive Biomarkers – Hgb A1c – My Interview with Dr. Russell Jaffe

hsHgb A1c is a marker of insulin resistance and when it is elevated, that means the body is no longer properly managing blood sugar levels. When this number is elevated, that also strongly suggests a tendency toward higher inflammation throughout the body. The graph below represents the correlation between Hgb A1c levels, blood glucose levels, and 10 year survival probability. Research has shown that insulin resistance and prediabetes can frequently be improved with diet and exercise. Hgb A1C provides a reliable test to evaluate the effects of dietary and nutritional support programs.

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222 – Nutrition for Healthy Eye Support – My Interview with Neil Levin

There have been numerous scientific and clinical studies that have revealed the benefits of certain nutrients for eye health and specifically AMD and the history of some of these studies is revealing. The studies that more experts refer to is called AREDS and AREDS-2. (Age-Related Eye Disease Study). These two studies were sponsored by the National Eye Institute (NEI) of the National Institutes of Health (NIH). So these are serious studies. In a nutshell the studied revealed “Taking the formulation reduced the rate of advanced AMD in people at high risk by about 25 percent over a 6-year period.”

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221 – Cannabidiol (CBD) – Nutrient, Food or Drug? – My Interview with Stuart Tomc

This action by DEA is signaling a hard-line position on all cannabis products. It is perhaps only a shot across the bow of the hemp industry at this moment, but it certainly has many concerned and considering how to respond to the potential threat. Just to be clear, this is not an enforcement issue. CBD continues to be available in the marketplace, but it’s future is a little more obscure. For those who have discovered the benefits of CBD, then the concern that they may lose access to CBD is genuine. The risk that CBD may become an expensive pharmaceutical drug is possible.

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220 – Chemical Free Cleaning Using Just e-cloth and Water – My Interview with Al Coviello

Using just water, the results showed that e-cloths removed over 99% of bacteria, locking them away inside the cloths’ fibers, where the bacteria stay until the cloths are rinsed. Further test show that, after a rinse with hot water, e-cloth reintroduced just 0.01% of bacteria back onto a sterile surface. Think about that. Wipe over 99% of bacteria off surfaces and wash it away with hot water. The cloth does not cross contaminate. All without any chemicals. And superior results for surfaces. You really should try them and see for yourself.

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219 – Cinnamon for Blood Sugar Support – My Interview with Jolie Root

The story of cinnamon as a nutritional supplement is an interesting one. I am always intrigued by the back story of how a supplement comes to be understood and recommended for its health benefits. How is it that we know that cinnamon supports healthy glucose metabolism? How does it work? How well does it work? How much should one take? Are there different forms and quality of cinnamon supplements? These are the topics I will discuss with Jolie Root.

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218 – Nurturing Your Probiotic Environment – My Interview with Josée Fortin

In this interview I will be speaking with Josée Fortin, who is a naturopath from Canada. We will explore one of A Vogels products Molkosan. Molkosan is a prebiotic made from a concentrated whey rich in L+ Lactic Acid. Molkosan is one of Alfred Vogel’s original remedies. Made from whey obtained from organic milk, Molkosan is rich in a substance known as L+ lactic acid which is now known to support the growth of good gut bacteria. In this way, it acts as a prebiotic. It does this by creating the proper and desirable colon pH. Proper pH = happy bacteria which will flourish better. This is different from prebiotic fibers which serve as food for the bacteria. This is more about the environment of the gut. It is also important to note that bad bacteria do not like L+ lactic acid.

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