Neuroplasticity: what is it and why should you care?

Dr. Michael Smith

Brain Support

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on Brain Support

“Neuroplasticity, also known as brain plasticity, is an umbrella term that refers to changes in neural pathways and synapses due to changes in behavior, environment, neural processes, thinking, emotions, as well as changes resulting from bodily injury. Neuroplasticity has replaced the formerly-held position that the brain is a physiologically static organ, and explores how – and in which ways – the brain changes throughout life.

Neuroplasticity occurs on a variety of levels, ranging from cellular changes due to learning, to large-scale changes involved in cortical remapping in response to injury. The role of neuroplasticity is widely recognized in healthy development, learning, memory, and recovery from brain damage. During most of the 20th century, the consensus among neuroscientists was that brain structure is relatively immutable after a critical period during early childhood. This belief has been challenged by findings revealing that many aspects of the brain remain plastic even into adulthood.” Quote from Wikipedia. READ MORE

Ibrain_cellsn this interview with Dr. Michael Smith we will explore the role some of the emerging nutrients for brain health and neuroplasticity. Once we understand that our brains can be changed and that our thinking can improve, we can then explore the many nutrients that have potential benefits. It is critical to realize that we are nourishing the body. We are not treating disease. So just like a gardener who will adjust the environment of the plants, we can also adjust the environment of our brain. Proper nourishment and intelligent care will usually result in better outcomes. If you want your brain to function better you have to give it the nutrition to do it. Your process of discovery is to explore your many options, try them with consistent application and the evaluate. There is no one easy path to brain health. The best program or product is the one that works best for you.

Dr. Smith with discuss some of the most interesting nutrients that are emerging for better brain health. One is magnesium threonate. Magnesium threonate is the form of magnesium that can easily get into your brain. Most magnesium forms do not readily cross the blood brain barrier. This is an example of our the specific form of a nutrient can make a huge difference in outcomes. You will also hear my personal story with magnesium threonate. He discusses how magnesium threonate and other nutrients are extremely beneficial for migraines. Change the nutritional environment of your brain and wonderful things can happen.

About Dr. Michael Smith
The Supplement PyramidDr. Smith is the Senior health scientist and online personality for Life Extension — the world’s leading organization dedicated to extending the healthy human life span. Dr. Smith is an author and blogger, creates and conducts webinars and appears in informational health and wellness videos. His engaging ability to present complex medical topics, be it diabetes, migraines, food sensitivity or weight management, in a clear, conversational manner has won him a sizable following of anti-aging and disease-prevention enthusiasts. He is the author of The Supplement Pyramid. Get 16 different health assessment questionairs online at

About Life Extension Foundation
The Life Extension Foundation is one of the largest organizations dedicated to investigating every method of extending the healthy human life span. When seeking anti-aging therapies, health and nutrition, The Foundation has reported discoveries in the areas of atherosclerosis and stroke prevention, diabetes, prostate health, hormone replacement therapy, and other health concerns. The Life Extension Foundation is a nonprofit, tax-exempt organization whose goal is to conquer the aging process within the next decade. The Life Extension Foundation was officially incorporated in 1980, but its founder has been involved in anti-aging research since the 1960s.

About Life Extension Magazine
Life Extension MagazineLife Extension magazine is the monthly publication of the Life Extension Foundation. Members of Life Extension receive the magazine for free in addition to their other membership benefits.

Life Extension is the first to report new discoveries involving nutrition, hormones, and anti-aging supplements, including such news-making items as coQ10 and omega-3 fatty acids. In addition, Life Extension reports innovative findings concerning the diseases that threaten many of us, such as atherosclerosis, cancer and diabetes. With each issue, subscribers to Life Extensionmagazine receive potentially life-saving information they won’t find in most other publications.




Prevagen shows significant and consistent improvement in recent memory studies.

Brain Support

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Mark UnderwoodIn this interview I will discuss with Mark Underwood the development of Prevagen for memory and brain support. I know a lot of people who use Prevagen and have discovered that Prevagen does improve memory. There are many ways that people are adversely affected by memory and cognition challenges. There are many nutritional ways to support brain health and memory. It is important to remember (no pun intended) that each of the many nutrients that work in the brain is unique. Each nutrient is a specific compound that provides a specific benefit. For this reason one should consider the many options and explore how each of these nutrients affect you as a unique person with unique nutritional needs.

Prevagen offers a specific benefit in that it’s role is to limit calcium uptake by the cells of the brain. It replaces a specific protein that diminishes as we age. Increasing this specific protein has been shown to support brain and memory function. It can be useful at any age, and especially as we get older. Like all nutrients, Prevagen does not cure or treat disease. Food and supplements work by nourishing the body and brain. A body that is well-nourished will do better than one that isn’t. Prevagen nourishes the brain.

JellyfishIf you want to discover the benefits of Prevagen you should take it for 3 months. Go to the website and take the memory test before you begin Prevagen. Then take the test monthly during the three months. This will give you a more objective looked at the benefits. It is always good to have benchmarks to help you understand the benefits of what you do for your health. Since brain health can be subjective, doing these simple brain tests can offer an additional way to measure the benefits. It is also helpful to ask those around you, if they notice an improvement. If you want to know if a supplement will help you, you have to try it. Give it a fair trial. Be consistent and take the recommended dose for the three months. Then you can more accurately measure the result. Evaluate and go from there.

CLICK HERE to view research and studies on Prevagen
PrevagenPrevagen significantly improves memory. In a large three month double-blind, placebo-controlled study of participants over 40 years old who were experiencing some mild memory problems associated with aging, the Prevagen group significantly supported areas of cognitive function such as learning and word recall.

Prevagen improves memory in a 90 day study. A majority of study participants reported Prevagen noticeably improved practical areas of memory like remembering driving directions and recalling words in a conversation in 90 days.

Prevagen improves the quality of sleep. Over 90 days, people who reported sleeping seven hours per night or less, increased their amount of sleep by an average of 37 minutes per night. In addition, these people experienced fewer wake-ups during the night, on average.

As we age, we lose about 85,000 brain cells each day. In the United States, 10,000 baby boomers turn 50 every day. And although a touch of gray hair can look distinguished, there are other age-related issues that may be unwanted, such as the mild memory problems associated with aging. Your brain is made up of many small cells, and controls everything you do. To stay healthy your brain contains proteins that support brain health.

The body’s ability to naturally produce this protein slows down. When this happens you may start to experience difficulty with memory, focus and concentration. Prevagen helps support brain cells by supplementing the proteins with the patented ingredient apoaequorin and supports healthier brain function.

Researchers have discovered a protein that actually supports healthy brain function. For many years, researchers have known that the human brain loses cells throughout our lives, part of the natural process of aging. In fact, we lose about 85,000 brain cells per day, that is one per second, over 31 million brain cells every year! This impacts every aspect of your life … how you think and how you feel. Recently, scientists made a significant breakthrough in brain health with the discovery that apoaequorin can support healthy brain function, help you have a sharper mind and think clearer.

Prevagen Supports:

  • BrainHealthy Brain Function. Apoaequorin is in the same family of proteins as those found in humans, but it was originally discovered in one of nature’s simplest organisms — the jellyfish.
  • Sharper Mind. Now produced in a scientific process, researchers formulated this vital protein into a product called Prevagen®. Prevagen is clinically shown to help with mild memory problems associated with aging.
  • Better Memory. This type of protein is vital and found naturally in the human brain and nervous system. As we age we can’t make enough of them to keep up with the brain’s demands. Prevagen supplements these proteins during the natural process of aging to keep your brain healthy. Prevagen comes in an easy to swallow capsule. It has no significant side effects and will not interact with your current medication.
  • Clearer Thinking. Just how well does Prevagen work? In a computer assessed, double-blinded, placebo controlled study, Prevagen improved memory for most subjects within 90 days.

About Mark Underwood
Mark Underwood is a graduate of the University of Wisconsin at Milwaukee, where he earned his Bachelor’s degree. He is a founder and currently serves as the President of Quincy Bioscience, Inc., Quincy Animal Health, LLC and CalciGenix, LLC, biotechnology companies located in Madison, Wisconsin. Created from the same platform technology these companies each focus on the discovery, development and commercialization of novel technologies to address cognitive issues and other age-related health challenges. Mr. Underwood is the inventor on several patents related to compounds for the regulation of calcium in the nervous system and other health related applications. Mark has a BA in Psychology (neurochemistry) from the University of Wisconsin-Milwaukee.



146 – Whole Food MegaFood Vitamins – My Interview with Robert Craven

This interview is different than most of my previous interviews. I will discuss the how and why of MegaFood Food State Nutrients with Robert Craven, CEO of MegaFood. I have been a fan of MegaFood for a long time and I have used many of their products over the years. The purpose of this interview is to take a closer look at the MegaFood difference as a company and a product.

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145 – Black Elderberry Extract for Flu Support – My Interview with Dean Morris

Studies have found that elderberry eases flu symptoms like fever, headache, sore throat, fatigue, cough, and body aches. The benefits seem to be greatest when started within 24 to 48 hours after the symptoms begin. One study found that elderberry could cut the duration of flu symptoms by more than 50%. Lab studies have found that elderberry might be effective against H1N1, or swine flu.

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144 – The Anti-Cancer Properties of IP-6 – My Interview with Dr. Abulkalam Shamsuddin

Recently IP(6) has received much attention for its role in cancer prevention and control of experimental tumor growth, progression, and metastasis. In addition, IP(6) possesses other significant benefits for human health, such as the ability to enhance immune system, prevent pathological calcification and kidney stone formation, lower elevated serum cholesterol, and reduce pathological platelet activity.

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143 – Weight Loss and Omega-3 – My Interview with Dr. Christopher Mohr

Dr. Mohr is a recognized expert in weight loss, sports nutrition and training, fitness and exercise, inflammation, heart disease, prevention and treatment of overweight and obesity, whole food nutrition and dietary supplement use for disease prevention, essential fatty acids, fish oil supplementation, lifestyle changes for improved health and mental performance.

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142 – Stress, Anxiety and Insomnia – My Interview with Dr. Michael Murray

Everyone has stress. Even happy events are stressful. It is even more challenging if one has anxiety and/or insomnia. It is difficult to be happy and healthy if one is overburdened with stress. If you are anxious and don’t sleep well it is difficult for your body to recharge and remain energetic. There are powerful natural therapies and nutritional supplements that can provide profound benefit

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141 – Boosting Your Brain Power – My Interview with Dr. Thomas Shea

Clinical nutritional science has shown conclusively that supplements of specific nutrients can improve both structure and function of our brains,. Brain cells have been shown to be very receptive to certain nutrients. A brain that is well nourished will always do better than one that is nutrient deprived.

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140 – The Clinical Benefits of Korean Ginseng – My Interview with Gregg Noll

Ginseng is known as the world’s most powerful adaptogenic herb. It is also known as the “King of Herbs”. An adaptogenic herb is an herb that assists the body to adapt and adjust to maintain balance and optimal health. Ginseng is considered one of the wonder drugs of nature.

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139 – Omega-3 and Mental Health Research – My Interview with Capt. Joseph Hibbeln, MD

In this interview Dr. Hibbeln will describe some of his research and the important implications for mental health. His research at the time of this interview was to determine if omega-3 fatty acids can reduce suicide behaviors. He also discusses the role of omega-3 for depression and their importance to pregnant and nursing mothers as well as their children.

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