Understanding Hemoglobin A1c as a predictive blood test

Blood Sugar Support

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If you have blood sugar issues then you are likely to be familiar with the Hgb A1c blood test. Did you know that the higher your Hgb A1c, the lower your odds of living for another 10 years? Higher A1c values are predictive of future health challenges and even longevity.
In this interview, Dr. Russell Jaffe will introduce the concept of ‘predictive biomarkers’. Dr. Jaffe strongly suggests we could all know much more about our health status and future with 8 lab tests that serve as important predictive biomarkers. These tests provide a snapshot of your current health status which can guide your choice for therapy or preventive actions. You can
research these further by visiting The tests are A1c, CrP, Homocysteine, LRA, 1st AM Urine pH, Vitamin D, Omega-3 index and 8 oxo-guanine.predictive_biomarkers I have long been an advocate for benchmark blood testing. Dr. Jaffe points the way for using these predictive biomarkers as guide for moving us closer to optimal health. Spend a little time learning about the importance of these tests and how you can use to make better choices. You can view Dr. Jaffe’s presentation to the International Academy of Oral Medicine on YouTube. I recommend it.

This is our first interview is a series that will cover each one of the eight predictive biomarkers in detail.

Hgb A1c Basics:
Excerpt from “Hgb A1c is the test most often used to evaluate blood sugar, diabetic risk, and insulin resistance. A routine  blood glucose test measures the amount of glucose in the blood on a given day, at a given time. Blood glucose level reflects only activity over the previous 12 to 18 hours. In contrast, Hgb A1c indicates the average blood sugar level for the previous three months.

This is important because frequently patients have normal blood glucose on the particular day the test is run, but their Hgb A1c could be elevated. Day-to-day blood glucose levels can be distorted by exercise, meal timings, or other medications. More importantly, we do not see high blood glucose levels routinely until prediabetes is quite far advanced. Hgb A1c gives us a much more reliable indication of actual, immediate risk.

The least-risk goal for this marker is Hgb A1c <5 %.
hsHgb A1c is a marker of insulin resistance and when it is elevated, that means the body is no longer properly managing blood sugar levels. When this number is elevated, that also strongly suggests a tendency toward higher inflammation throughout the body. The graph below represents the correlation between Hgb A1c levels, blood glucose levels, and 10 year survival probability.

Research has shown that insulin resistance and prediabetes can frequently be improved with diet and exercise. Hgb A1C provides a reliable test to evaluate the effects of dietary and nutritional support programs.

Better Lab Tests Now
Better Lab Tests Now offers only the highest quality lab tests available and works exclusively with highly decorated labs that have been awarded in their field. All of the necessary research has been done for you. Their clear and straightforward system allows you to choose the tests you need without the hassle of dealing with insurance companies. They offer food intolerance tests, hormone tests, and more. Please note that testing cannot be ordered from the states of New York, New Jersey, Rhode Island, Massachusetts, and Maryland due to those states’ laws prohibiting direct access testing for their residents. We hope this will change in the future. If you live in one of these states, contact your legislators and express your opinion about these restrictions on your access to these life enhancing tests.

Contact PERQUE Integrative – 800.525.7372. Here you can learn more about finding a PERQUE trained practitioner, research the 8 Predictive Biomarkers and research PERQUE products.

About Dr. Jaffe
Dr. Russell M. Jaffe received his BS, MD and Ph.D from the Boston University School of Medicine in 1972. He completed residency training in clinical chemistry at the National Institutes of Health (1973 – 1976), remaining on the permanent senior staff until 1979. He is board certified in Clinical Pathology and in Chemical Pathology. On leaving NIH Dr. Jaffe began a journey that sought to support the emerging field of Integrative and Regenerative Medicine.

Dr. Jaffe is CEO and Chairman of PERQUE Integrative Health (PIH). His dedication to the application of primary prevention and his commitment to providing superior nutraceuticals and autoimmune testing with clinical evidence of superior efficacy has made him a sought after speaker and leader in his chosen field. You can learn more about Dr. Jaffe and read some of his work here.




Protecting your eyes and vision.

Eye Support

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When I was younger, I remember that the common wisdom was that eating carrots was good for your eyes. That was about it. The opinion of the medical community was that nutrition, diet and/or supplementation was not beneficial for eye health and was in fact a waste of money. Of course, this was no different that the medical wisdom of 45 years ago which said just eat the standard American diet and you would be just fine. We know now that that advice was ignorant and ill-informed. Science is finally revealing the benefits of nutrition throughout the human system including the eyes. Doesn’t just make sense that tissues that are well nourished will do better that those that are not? People will do better when they are well nourished.

When it comes to vision and eye health, people are very concerned, especially as we age. Fear of losing one’s sight is a common anxiety for many  people, again especially seniors. This becomes critical when one is facing issues such as age-related macular degeneration (AMD). The question is “can nutrition (diet and/or supplementation) have a positive affect on AMD?” I need to reemphasize that nutrition does not treat or cure any eye disease including AMD. What food and supplements do is deliver nutrients to the body. It is the body that uses nutrients to maintain and normalize cellular and tissue function. Let the doctors treat your disease. You should focus on nourishing your body with the specific nutrients that have been shown to provide the benefits you seek. Drugs do not nourish the body and nutrients are not drugs. Please don’t confuse the two. You will have more success when you understand this distinction.

There have been numerous scientific and clinical studies that have revealed the benefits of certain nutrients for eye health and specifically AMD and the history of some of these studies is revealing. The studies that more experts refer to is called AREDS and AREDS-2. (Age-Related Eye Disease Study). These two studies were sponsored by the National Eye Institute (NEI) of the National Institutes of Health (NIH). So these are serious studies. In a nutshell the studied revealed “Taking the formulation reduced the rate of advanced AMD in people at high risk by about 25 percent over a 6-year period.” You can read more here.

Here is a quote from the American Optometric Association:

Adding powerful antioxidants to your diet can improve your eye health.
There’s no substitute for the quality of life good vision offers. Adding certain nutrients to your daily diet—either through foods or supplements—can help preserve your vision. Researchers have linked eye-friendly nutrients, such as lutein and zeaxanthin, vitamin C, vitamin E and zinc, to reducing the risk of certain eye diseases.

  • Lutein & Zeaxanthin – Lutein and zeaxanthin are important nutrients found in green leafy vegetables, as well as other foods, such as eggs. Many studies show that lutein and zeaxanthin reduce the risk of chronic eye diseases, including age-related macular degeneration and cataracts.
  • Vitamin C – Vitamin C (ascorbic acid) is an antioxidant found in fruits and vegetables. Scientific evidence suggests vitamin C lowers the risk of developing cataracts. Also, when taken in combination with other essential nutrients, it can slow the progression of age-related macular degeneration and visual acuity loss.
  • Vitamin E – Vitamin E is a powerful antioxidant found in nuts, fortified cereals and sweet potatoes. Research indicates it protects cells in the eyes from unstable molecules called free radicals, which break down healthy tissue.
  • Essential Fatty Acids – Fats are a necessary part of the human diet. They maintain the integrity of the nervous system, fuel cells and boost the immune system. Research shows omega-3 fatty acids are important for proper visual development and retinal function.
  • Zinc – Zinc is an essential trace mineral or “helper molecule.” It plays a vital role in bringing vitamin A from the liver to the retina in order to produce melanin, a protective pigment in the eyes. Zinc is highly concentrated in the eye, mostly in the retina and choroid, the vascular tissue layer lying under the retina. End quote

In this interview, Neil Levin discusses eye health and the science of nutrition and AMD. We will also discuss the NOW product called Ocu Support (formally Eye Support). Ocu Support has been formulated to offer comprehensive nutritional protection for the eyes. Each serving has 10 mg of available Lutein, a critical pigment of the macula, lens, and other ocular tissues. Lutein is a free-radical scavenger related to beta-carotene that defends the eye from the ravages of sunlight. NOW has also included Green Tea Extract, Alpha Lipoic Acid and Grape Seed Extract in this formula to maximize its free radical scavenging potential.

About Neil Levin
Neil E. Levin, CCN, DANLA is the Senior Education Manager and a product formulator for NOW® Foods. He is a board-certified clinical nutritionist with a diplomate in advanced nutritional laboratory assessment. The U.S. Natural Products Association (NPA) presented Neil its Industry Champion Award in 2008 for “people who have made notable individual contributions to the natural products industry above and beyond what is expected to achieve commercial success.”

Neil’s interviews and articles are published in magazines and newspapers. He has been featured in many radio interviews and television news reports. Neil blogs at; is on Facebook (Honest Nutrition) and Twitter (neilelevin).

About NOW Foods
Founded by Elwood Richard in 1968 on the belief that natural is better, NOW has grown from a small family operation into one of the most highly respected manufacturers in the natural products industry. Still a family-owned company today, NOW offers more than 1,400 dietary supplements, foods, sports nutrition and personal care products. NOW is committed to offering safe, affordable products of the highest quality, and is a highly regarded advocate in the natural products industry. Its state-of-the-art manufacturing facility in Bloomingdale, Ill., has been GMP (Good Manufacturing Practice)-certified since 2000 and its in-house laboratory capabilities are among the best in the industry. The company has over 1400 employees, and its products are sold in more than 60 countries. After nearly 50 years in the natural products industry, NOW remains committed to its original mission – to provide value in products and services that empower people to lead healthier lives.


221 – Cannabidiol (CBD) – Nutrient, Food or Drug? – My Interview with Stuart Tomc

This action by DEA is signaling a hard-line position on all cannabis products. It is perhaps only a shot across the bow of the hemp industry at this moment, but it certainly has many concerned and considering how to respond to the potential threat. Just to be clear, this is not an enforcement issue. CBD continues to be available in the marketplace, but it’s future is a little more obscure. For those who have discovered the benefits of CBD, then the concern that they may lose access to CBD is genuine. The risk that CBD may become an expensive pharmaceutical drug is possible.

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220 – Chemical Free Cleaning Using Just e-cloth and Water – My Interview with Al Coviello

Using just water, the results showed that e-cloths removed over 99% of bacteria, locking them away inside the cloths’ fibers, where the bacteria stay until the cloths are rinsed. Further test show that, after a rinse with hot water, e-cloth reintroduced just 0.01% of bacteria back onto a sterile surface. Think about that. Wipe over 99% of bacteria off surfaces and wash it away with hot water. The cloth does not cross contaminate. All without any chemicals. And superior results for surfaces. You really should try them and see for yourself.

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219 – Cinnamon for Blood Sugar Support – My Interview with Jolie Root

The story of cinnamon as a nutritional supplement is an interesting one. I am always intrigued by the back story of how a supplement comes to be understood and recommended for its health benefits. How is it that we know that cinnamon supports healthy glucose metabolism? How does it work? How well does it work? How much should one take? Are there different forms and quality of cinnamon supplements? These are the topics I will discuss with Jolie Root.

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218 – Nurturing Your Probiotic Environment – My Interview with Josée Fortin

In this interview I will be speaking with Josée Fortin, who is a naturopath from Canada. We will explore one of A Vogels products Molkosan. Molkosan is a prebiotic made from a concentrated whey rich in L+ Lactic Acid. Molkosan is one of Alfred Vogel’s original remedies. Made from whey obtained from organic milk, Molkosan is rich in a substance known as L+ lactic acid which is now known to support the growth of good gut bacteria. In this way, it acts as a prebiotic. It does this by creating the proper and desirable colon pH. Proper pH = happy bacteria which will flourish better. This is different from prebiotic fibers which serve as food for the bacteria. This is more about the environment of the gut. It is also important to note that bad bacteria do not like L+ lactic acid.

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217 – Aged Garlic Extract for Cardiac Health – My Interview with James LaValle

Cardiac health is a huge concern. How does one maintain and improve cardiac health? There are many products available to support cardiac health. How does one choose? Look for products that can confirm the benefits through science. Its why I get excited about AGE. Its why I want you to know more about this amazing product.
What is Aged Garlic Extract?
GarlicMost people think garlic is garlic. Not so. AGE is the only truly odorless garlic supplement. The garlic used is grown organically and cultivated to enhance it’s beneficial constituents and for quality standards. The garlic is cleaned and sliced and then aged in stainless steel tanks for up to 20 months. In this process the garlic is changed. The harsh compounds become mild and odorless and are converted to the beneficial natural compounds that are responsible for AGE’s unique properties. AGE and it’s various constituents have been the subject of over 750 scientific publications around the world including Japan, the U.S., South America and Europe since its development in 1955.

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216 – Fast Acting Natural Boost for Your Immune Function – My Interview with Lester Burks

In our interview I will discuss ACF Fast Relief with Lester Burks, Chief Managing Office of Life Line Foods. Life Line Foods is the manufacturer of the Buried Treasure line of liquid supplements. They have about 35 products and we are going to discuss one specialized formula – ACF Fast Relief. ACF Fast Relief is a liquid formula of vitamins, minerals, herbs and silver. It is a product that has been a mainstay in health food stores for decades. It is a liquid that you take four times a day beginning at the first sign of an attack.

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215 – Probiotic Support for Irritable Bowel Syndrome – My Interview with Dr. Anurag Pande

In this interview Dr. Pande will discuss some of the issues with probiotics in general. If you are an informed consumer then you know that there are many products that are low quality and low effectiveness that exist in the marketplace. We have discussed these issues in previous podcasts. The solution is to understand the distinctions and seek out high quality products with clinical science to validate their claims.

In this case we are discussing the clinical evidence for IBS and Lactospore. Lactospore is also a unique probiotic in the manner in which it protects itself and that it is heat stable. It can even be used in baked goods and still remain viable. That’s a first for me. Heat is usually destructive to probiotics. So this is an interesting exploration of a novel probiotic. Dr. Pande explains this very well.

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214 – Is Inflammation Caused by a Repair Deficit? – My Interview with Dr. Russell Jaffe

Inflammation is not a disease. It is a result of the body’s attempt to heal. When we use targeted nutrition, we are giving the body the specific nutrients to facilitate repair. Dr. Jaffe’s research has led to our understanding of the role of specific antioxidants for inflammation repair.

“Inflammation is like a smoldering fire that eventually eats through the fiber of our being. Because it affects the connective tissue infrastructure upon which our bodies are built, repair deficits can occur in any part of the body that is stressed, lacking in nutrients, or more exposed to toxins. This makes inflammation an underlying co-morbidity for many ills.

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