The benefits of systemic metabolic enzymes are profound.

Tom Bohager

Inflammation & Pain Support

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I recently interviewed Tom Bohager about the role of digestive enzymes. I consider digestive enzymes to be one of the top two supplements for anyone with digestive challenges, the other being probiotics. One of the things that surprised me in that interview was that digestive enzymes are still not that well known or understood by consumers. When you consider the number of people with digestive challenges, one would think that digestive enzymes would be a first line consideration. They should be. You can learn more about digestive enzymes in my previous interview with Tom.

In this interview with Tom, we are going to discuss metabolic enzymes (also known as therapeutic enzymes). I am certain that many less consumers know about or understand this part of the enzyme story. This also surprises me because the research on metabolic enzymes goes back 50 years. I have known about and used some form of enzymes for nearly 40 years and we always have some in our natural medicine chest. I consider them to be a very important adjunct nutrient for pain and inflammation. Metabolic enzymes are those enzymes that are taken for purposes other than digestion. For that reason metabolic enzymes are taken between meals on an empty stomach.

Perhaps the most common use of metabolic enzymes is for pain and inflammation. Especially for short term pain related to activity. Other uses include nattokinase for cardiac support and cellulase for candida yeast problems.

What Are Enzymes? Excerpted from



Enzymes are biologically active proteins found in all living cells.  Metabolic enzymes catalyze and regulate every biochemical reaction that occurs within the human body, making them essential for cellular function and overall health.  Digestive enzymes turn the food we eat into energy which may be utilized by the body for various biological processes.  Our bodies naturally produce both digestive and metabolic enzymes, as they are needed.

Enzymes are protein chemicals, which carry a vital energy factor needed for every chemical action, and reaction that occurs in our body. There are approximately 1300 different enzymes found in the human cell. These enzymes can combine with coenzymes to form nearly 100,000 various chemicals that enable us to see, hear, feel, move, digest food, and think. Every organ, every tissue, and all the 100 trillion cells in our body depend upon the reactions of metabolic enzymes and their energy factor. Nutrition cannot be explained without describing the part that enzymes play.

Pain and InflammationHow are enzymes utilized in the body?

  • Metabolic Enzymes are an essential component for optimal cellular function and health. These descriptions are not without merit. They speed up the chemical reactions within the cells for detoxification and energy production. They enable us to see, hear, feel, move and think. Every organ, every tissue and all 100 trillion cells in our body depend upon the reaction of metabolic enzymes and their energy factor. Without these metabolic enzymes, cellular life would cease to exist.
  • Digestive Enzymes are secreted along the digestive tract to break food down into nutrients and waste.
  • Food Enzymes are introduced to the body through the raw foods we eat and through consumption of supplemental enzyme products. Raw foods naturally contain enzymes, providing a source of digestive enzymes when ingested. However, raw food manifests only enough enzymes to digest that particular food. The cooking and processing of food destroys all of its enzymes.

A variety of supplemental enzymes are available through different sources. It is important to understand the differences between the enzyme types and make sure you are using an enzyme product most beneficial for your particular needs. With most supplements, we are used to comparing products based on weight.  However, with enzymes we are interested in the activity and potency available.  It is important to recognize that there is no direct relationship between weight and enzyme activity.   End excerpt.

As I mentioned we use enzyme supplements all the time in our home. We use digestive enzymes because we feel better after a meal. I take nattokinase daily to reduce my risk of blood clots. I don’t have a problem; it is my way of being proactive and preventive. We will use other enzymes when needed for short term pain, swelling and inflammation that we all get on occasion. It will be helpful if you learn more about the benefits of enzymes both digestive and metabolic. Most people will do better with at least a digestive enzyme with every major meal.

About Tom Bohager
Enzymes_BohagerTom Bohager holds a bachelor’s degree in holistic nutrition from Clayton College of Natural Health and is the author of two books: Everything You Need to Know About Enzymes, (2008), and Enzymes: What the Experts Know (2006).

In 1998 Tom received extensive training at the Transformation Enzyme Therapy center in Houston Texas. In that same year he started Enzymedica in an effort to educate and help as many people as possible on the benefits of high potency enzymes and enzyme therapy. In addition to focusing on Enzymedica’s long-range goals Tom founded The Autism Hope Alliance in 2008. Tom currently focuses his primary efforts on Enzymedica as its Chairman while supporting The Autism Hope Alliance as its founder.








47 Clinical Studies Confirm the Benefits of Curcumin C3 Complex


Inflammation & Pain Support

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Curcumin (turmeric extract) has become one of the fastest growing and likely most beneficial herbs we have. With good reason: Curcumin exerts its benefits across a wide range of health conditions. Because its role in calming inflammation is so dramatic and the science is so compelling curcumin has become one of the worlds most important herbal extracts. Its popularity is unrivaled among herbs at this  point in time.

Because of this popularity, there are many sources of curcumin on the market. Many of these sources are providing curcumin extracts that have virtually no clinical evidence for their safety or effectiveness. How do we as consumers have confidence in a product? How do we know if a particular form of curcumin is effective and safe? We now know that there are synthetic analogs of curcumin that are very difficult to detect using traditional methods. The cheaters are very sophisticated. So how do we identify effective products?

When we take supplements, we all want to get the benefits that we have heard about. We know what the benefits are because some of the extracts have been clinically studied. The studies reveal the safety. The studies reveal the benefits. The studies reveal the effective dosage. The studies verify no toxicity. This is how we know and have confidence in particular products. My goal is to help you identify good companies with good science.

C3_ComplexWhen we want to understand the benefits of curcumin we can look to Sabinsa C3 Complex. This particular curcumin extract has 47 clinical studies going back to 1998. This is more than any other curcumin product. In this interview, I am speaking to Dr. Anurag Pande, PhD about these scientific studies using C3 Complex.

“The Role of Inflammation
Most degenerative diseases are driven by chronic, sub-clinical inflammation. The old view of inflammation is that it represents the healing process. This is true to a certain extent; however when inflammation becomes chronic, it becomes a disease.

Today the study of inflammation has gone from the tissue levels deeper into the nuclear level. Cell-signaling molecules have been identified which stimulate the genes that induce the expression of the COX enzyme, which in turn induces inflammation.

InflammationBeneficial Effects of Curcuminoids

  • Curcumin C3 Complex is an effective “Bioprotectant”, antioxidant quenching free radicals and also preventing their formation.
  • Curcumin has been shown to be a COX 2 (Cyclooxygenase-2) inhibitor.
  • Unlike conventional non steroidal anti-inflammatory drugs (NSAIDs), curcuminoids do not cause gastrointestinal side effects or ulcers.
  • Curcuminoids support a healthy immune system
  • Prevent connective tissue break down through inhibiting destructive enzymes

Nutraceutical Applications of Circurcuminoids

  • Curcumin_BenefitsAntioxidant support
  • Alzheimer’s disease/dementia
  • Cardiovascular support
  • Immune support/ Anti-tumor/Anticancer effects  Anti-inflammatory support
  • Wound healing for example: Rheumatoid arthritis, postoperative inflammation, colorectal cancer, bladder cancer, oral leucoplakia, psoriasis, antiviral effects.” Excerpt from

About Dr. Anurag Pande, PhD
Curry Powder to Clinical SignificanceDr. Pande is the Vice-President of Scientific Affairs for Sabinsa. Dr. Pande holds a Ph.D. in Phytochemistry. He has both a Masters Degree in Science and a Bachelor’s Degree in Science. He is the author of several trade and peer reviewed publications. He is a contributor to the book “Curry Powder to Clinical Significance”.

Dr. Pande has been with Sabinsa’s sister company, Sami Labs, since 2004 in a research capacity, and spent several years at Sabinsa Japan’s Tokyo office as Senior Technical Manager. Today, Dr. Pande works from Sabinsa’s Corporate HQ based in East Windsor, NJ, USA.

About Sabinsa
Sabinsa Corporation, founded in 1988, is a manufacturer and supplier of herbal extracts, cosmeceuticals, minerals and specialty fine chemicals. Sabinsa’s mission is to provide alternative and complementary natural products for human nutrition and well-being. Over the past twenty years, Sabinsa has brought to market more than 100 standardized botanical extracts and privately funded several clinical studies in conjunction with prestigious institutions in support of these products. Its present operations have grown to employ 1000 people worldwide in ten manufacturing, R&D and distribution facilities. Additionally, botanical cultivation efforts undertaken by the organization now total nearly 40,000 acres to ensure sustainable supplies on its key products. All products intended for human consumption are certified Kosher and Halal.



202 – Is PQQ The Next Nutrient Superstar? – My Interview with Dr. Michael Murray

What are the clinical uses of PQQ? Given the nutritional importance and tremendous span of physiological effects of PQQ, there are considerable benefits in conditions that revolve around low mitochondrial function including in aging, many brain and neurological disease (e.g., Alzheimer’s and Parkinson’s disease), and many other chronic degenerative disease. Current research has primarily focused on its ability to protect memory and cognition in both aging animals and humans.

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201 – Traditional Chinese Medicine (TCM) – My Interview with David Jones

Traditional Chinese medicine is a style of traditional Asian medicine informed by modern medicine but built on a foundation of more than 2,500 years of Chinese medical practice that includes various forms of herbal medicine, acupuncture, massage (tui na), exercise (qigong), and dietary therapy. It is primarily used as a complementary alternative medicine approach. TCM is widely used in China and is becoming increasingly prevalent in Europe and North America.

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200 – The Good, The Bad and The Ugly – My Opinion – Steve Lankford

The nutritional products industry is rapidly changing. In some ways it is a victim of its own success. Those who have been in the industry a long time, like me with over 40 years, have wanted good nutrition to become widely accepted. Now that better nutrition is being embraced by a much larger community, we have many new participants in the marketplace, from more consumers, to more mass market and internet access, more product manufacturers, more raw material suppliers and so on. The business of nutrition is changing in ways that are not obvious to the average consumer. In this podcast, I will discuss some of the important issues that I think you should know about. They are issues that affect us now and will shape the future. There is much good to discuss and celebrate in the world of nutrition. There is also the bad to be concerned about and avoided. And the ugly is that which is evil and dishonest.

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199 – Nattokinase and Cardiovascular Health – My Interview with Dr. Ralph Holsworth

NattokinaseIn this interview, Dr. Holsworth will discuss the origins of nattokinase and the emerging science that reveals the benefits. The basic issue here is that fibrin is the factor in our blood that forms blood clots. Too much fibrin thickens the blood increasing one’s risk of cardiovascular disease. Consumption of nattokinase has been shown to enhance fibrinolytic activity leading to reduced fibrin in the blood. Nattokinase has also shown benefits for blood pressure support. Here is a quote from Dr. Holsworth’s paper:

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198 – Garlic Extract Reverses Heart Disease – My Interview with Dr. Matthew Budoff

We all want good science to validate the products we use. For the best results follow the science. My guest is Dr. Matthew Budoff. Dr. Budoff has completed 4 clinical studies on Aged Garlic Extract. I have interviewed him after each interview and if you want to follow the evolution of this science, you can listen to all of those interviews here. You can follow Dr. Budoff’s journey from skeptic to confident proponent. The science and the results are compelling.

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197 – A Call for Probiotics – My Interview with Jolie Root

The average consumer is usually years behind current research. It takes years for a nutrient to emerge into the general awareness. Consider the emergence of probiotics. What is now known by many consumers is that probiotics are beneficial for digestive health . We now know this based on previous research done years, even decades, in the past. In this interview with Jolie Root you are going to learn about some of the current leading edge research with probiotics.

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196 – The Immune Benefits of Mushrooms

Mushrooms are now being rediscovered for both their nutritional and health supporting benefits. For many years the only mushrooms that most of us were familiar with are the common white button mushrooms found in the supermarket. The past 20-30 years has seen a surge of scientific inquiry into the nutritional components of many different mushrooms. We now have much more respect for powerful health giving benefits provided by mushrooms.

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195 – Liposomes for Nutrient Delivery – My Interview with Dr. Emek Blair

Liposomes are basically a nutrient wrapped in a layer of fat (phosphatidylcholine, an important beneficial fat molecule). This is the same way that nutrition is delivered to babies through breast milk. Little fat bubbles fulled with nutrients. Liposomes are sometimes used with drugs to deliver drugs to specific targets in the body. Liposomes are also used to deliver nutrients into the body. Liposomes are better at carrying nutrients into the body and also delivering that nutrient into the cell than powders which make up most tablets and capsules. The phosphatidylcholine part of the liposome is then added as a healthy fat to cell membranes. These are important distinctions that determine how well your supplements are absorbed and utilized.

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